| Course title | Biochemistry 2 |
|---|---|
| Course code | LCH/VAA22 |
| Organizational form of instruction | Lecture + Exercise + Seminar |
| Level of course | Master |
| Year of study | not specified |
| Semester | Winter |
| Number of ECTS credits | 7 |
| Language of instruction | English |
| Status of course | Compulsory |
| Form of instruction | Face-to-face |
| Work placements | This is not an internship |
| Recommended optional programme components | None |
| Course availability | The course is available to visiting students |
| Lecturer(s) |
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| Course content |
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Main topics covered within this subject will be: 1. Blood plasma lipids. Lipoprotein metabolism. Disorders of lipoprotein metabolism. 2. Insulin and glucagon metabolism. Effect on metabolism. Pathobiochemistry of lipid and carbohydrate metabolism. 3. Biochemical processes in the digestive tract. 4. Metabolic functions of the liver. Catabolism of heme (tetrapyrroles). 5. Metabolism of xenobiotics and ethanol. Iron and copper metabolism. 6. O2 and CO2 transport. Sodium and potassium homeostasis. Acid-base balance (ABB). 7. Biochemical function of kidneys. Biochemistry of nervous tissue. Biochemistry of neural transmission. 8. Neurosecretion. Cerebrospinal fluid. Neurodegenerative diseases. Biochemistry of vision. 9. Nutrition. Overview of nutrient metabolism under different conditions. 10. Extracellular matrix - proteins. Biochemistry of bone. Osteosynthesis. Biochemistry of connective tissue and skin. 11. Biochemistry of muscle activity. Metabolic processes in the myocardium. 12. Metabolism of calcium, magnesium, phosphate and fluoride. Iodine metabolism. Synthesis of thyroid hormones. 13. Biochemistry of blood elements. The most important proteins of the blood plasma. 14. Biochemical processes in the body - summary.
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| Learning activities and teaching methods |
| Monologic Lecture(Interpretation, Training), Dialogic Lecture (Discussion, Dialog, Brainstorming), Work with Text (with Book, Textbook), Demonstration |
| Learning outcomes |
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The aim of the subject is to explain the principles of biochemical processes in the organism and the mechanisms of regulation of basic metabolic events. This knowledge is a prerequisite for the interpretation of physiological and pathological processes in the human organism. Students are also guided to practical mastery of simple biochemical analyzes and to the interpretation of laboratory test results.
The student who passes the subject will be equipped with theoretical knowledge on basic biochemical pathways and information on regulation of intermediary metabolism. Student will be able to interpret physiological and pathological events in human organism. In practice, student will be able to work according to good laboratory practice rules and to perform basic biochemical tests and to interpret laboratory results. |
| Prerequisites |
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Successfully passing subjects Medical biology, Normal anatomy, and credit in Biochemistry 1.
LCH/VAB11 ----- or ----- LCH/VAB20 and NAN/VAB12 ----- or ----- NAN/VAB13 and NAN/VAA12 ----- or ----- NAN/VAA13 and CJA/VA031 and BIO/VAB11 ----- or ----- BIO/VA011 and CJA/VAB12 ----- or ----- CJA/VAB41 and HIE/VAB11 ----- or ----- HIE/VAB12 and KAR/VAB11 and LBF/VAB11 ----- or ----- LBF/VA011 and PVL/VAB12 ----- or ----- PVL/VAB32 and PLE/VAA11 ----- or ----- PLE/VAB81 and PLE/VAB11 ----- or ----- PLE/VAB81 and CJA/VAA12 ----- or ----- CJA/VAA41 |
| Assessment methods and criteria |
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Written exam, Didactic Test
100% participation in practical exercises, credit test, written exam |
| Recommended literature |
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| Study plans that include the course |
| Faculty | Study plan (Version) | Category of Branch/Specialization | Recommended semester | |
|---|---|---|---|---|
| Faculty: Faculty of Medicine and Dentistry | Study plan (Version): General Medicine (2025) | Category: Medical sciences | 2 | Recommended year of study:2, Recommended semester: Winter |