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Lecturer(s)
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Zapletalová Jana, Mgr. Dr.
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Sněhota Martin, MUDr. Mgr. Ph.D.
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Bajgar Robert, MUDr. Mgr. Ph.D.
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Binder Svatopluk, Mgr. Ph.D.
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Langová Kateřina, Mgr. Ph.D.
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Bartoň Tománková Kateřina, doc. Ing. Ph.D.
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Malina Lukáš, Mgr. Ph.D.
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Hošíková Barbora, Mgr. PhD.
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Dilenko Hanna, Mgr.
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Kolářová Hana, prof. RNDr. CSc.
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Vachutka Jaromír, Mgr. Ph.D.
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Course content
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Introduction to medical biophysics. Molecular structure of living systems. Cell biophysics. Electromagnetic spectrum. Radiation sources. Optical instruments in medicine. Biophysics of vision. The optical system of the human eye, refractive disorders and their correction. Biosignals, generation, processing, analysis. Fundamentals of biomechanics. Sound and its properties. Human voice. Biophysics of hearing. Biophysics of electric manifestations in organism, and their use in therapy. Biophysics of respiration. Biophysics of blood circulation. Microscopical methods. Ultrasound methods in medicine. Therapeutic ultrasound application in medicine. Ionizing radiation in medicine. Magnetic resonance. Positron emission tomography and other imaging methods of nuclear medicine. Nanotechnology in medicine. Environmental biophysics. Fundamentals of measurement. Essentials of informatics, medical informatics. Introduction to biostatistics. Sampling and descriptive statistics. Hypothesis testing, parametric tests. Non-parametric tests, categorical data analysis, dependency measurement.
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Learning activities and teaching methods
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Lecture, Monologic Lecture(Interpretation, Training), Dialogic Lecture (Discussion, Dialog, Brainstorming), Laboratory Work
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Learning outcomes
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The goal of the subject is an explanation of biophysical principles in the physiological processes of the human body (molecular biophysics, biophysics of cell and tissues), its function (biophysics of perception, organ biophysics) and its interaction with the external environment. It explains the basic principles of diagnostic and therapeutic instruments, essentials of biocybernetics, biostatics, computer techniques and informatics focusing on hospital systems. The basic goal of the practical training is to develop in students the general routine needed at work with medical instrumental techniques. A part of the practical training course is a computer work, when the students are familiarized with application software used in medicine.
The students will be able to understand biophysical processes in human body and will be able to work with basic medical instrumental technique. The students will be prepared for further study of consequent subjects like physiology, pathophysiology, radiology, nuclear medicine etc. Their knowledge on informational technologies support them in effective use of medical software (e.g. software focused on image analysis) or work in hospital information systems. Students will also be able to statistically evaluate various biomedical data.
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Prerequisites
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Students ought to have fundamental biology and physics attainments at the secondary education level.
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Assessment methods and criteria
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Mark, Oral exam, Written exam
Successfully completed all practical tutorials and measurement protocols elaborated, final exam in a written form (MCQ, calculations, essay questions).
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Recommended literature
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Davidovits, P. (2013). Physics in Biology and Medicine. Academic Press.
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Herman, I.P. (2015). Physics of the Human Body. Springer.
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Hobbie, R. K., & Roth, B. J. (2007). Intermediate physics for medicine and biology. New York: Springer.
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Keevil, S., Padovani, R., Tabakov, S., Greener, T. (2022). Cornelius Lewis Introduction to Medical Physics. CRC Press.
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Wood, A.W. (2012). Physiology, Biophysics and Biomedical Engineering. CRC Press.
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