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Main menu for Browse IS/STAG
Course info
KFC / STBI
:
Course description
Department/Unit / Abbreviation
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KFC
/
STBI
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Academic Year
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2018/2019
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Academic Year
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2018/2019
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Title
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Structural Bioinformatics
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Form of course completion
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Exam
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Form of course completion
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Exam
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Accredited / Credits
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Yes,
2
Cred.
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Type of completion
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-
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Type of completion
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-
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Time requirements
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Přednáška
1
[Hours/Week]
Seminar
1
[Hours/Week]
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Course credit prior to examination
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No
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Course credit prior to examination
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No
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Automatic acceptance of credit before examination
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No
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Included in study average
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YES
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Language of instruction
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Czech, English
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Occ/max
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Automatic acceptance of credit before examination
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No
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Summer semester
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0 / -
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0 / -
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0 / -
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Included in study average
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YES
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Winter semester
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3 / -
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0 / -
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0 / -
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Repeated registration
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NO
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Repeated registration
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NO
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Timetable
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Yes
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Semester taught
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Winter semester
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Semester taught
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Winter semester
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Minimum (B + C) students
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not determined
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Optional course |
Yes
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Optional course
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Yes
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Language of instruction
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Czech, English
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Internship duration
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0
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No. of hours of on-premise lessons |
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Evaluation scale |
A|B|C|D|E|F |
Periodicity |
každý rok
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Periodicita upřesnění |
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Fundamental theoretical course |
No
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Fundamental course |
No
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Fundamental theoretical course |
No
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Evaluation scale |
A|B|C|D|E|F |
Substituted course
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None
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Preclusive courses
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N/A
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Prerequisite courses
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N/A
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Informally recommended courses
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N/A
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Courses depending on this Course
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N/A
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Histogram of students' grades over the years:
Graphic PNG
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XLS
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Course objectives:
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Structural bioinformatics is a part of bioinformatics, which is related to the analysis and prediction of the three-dimensional structure of biomacromolecules for the analysis of their function.
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Requirements on student
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Structural bioinformatical analysis of model system, discussion on a given topic (2 questions)
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Content
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Description of biomacromolecules, Structural hierarchy, proteins, nucleic acids Structure determination (X-Ray, NMR, EM, etc.) Structure file formats PDB database NDB database Other structural databases (CATH, SCOP, Drugbank) Vizualization of structure, structural alignment Structure prediction, CASP Function prediction Ligand docking Challenges of structural bioinformatics - membrane proteins, nucleic acids, protein-protein interactions prediction
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Activities
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Fields of study
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Guarantors and lecturers
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-
Guarantors:
doc. RNDr. Karel Berka, Ph.D. (100%),
-
Lecturer:
doc. RNDr. Karel Berka, Ph.D. (100%),
RNDr. Miroslav Krepl (100%),
Mgr. Petra Kührová, Ph.D. (100%),
Mgr. Marie Zgarbová, Ph.D. (100%),
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Seminar lecturer:
doc. RNDr. Karel Berka, Ph.D. (100%),
RNDr. Miroslav Krepl (100%),
Mgr. Petra Kührová, Ph.D. (100%),
Mgr. Marie Zgarbová, Ph.D. (100%),
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Literature
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Basic:
Bourne P. & Helge W. (Eds.). Structural Bioinformatics. Wiley, 2003.
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Basic:
Zvelebil, M. & Baum, J. Understanding Bioinformatics. Garland Science, 2007.
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Recommended:
Voet D. & Voet JG. Biochemistry (3rd edition). Wiley, 2004.
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Recommended:
Orengo CA., Jones DT., Thornton JM. (Eds.). Bioinformatics - Genes, Proteins and Computers. Bios Scientific Publishers Ltd., 2003.
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Recommended:
Leach AR. Molecular Modelling - Principles and Applications (2 edition). Pearson Education, 2001.
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Recommended:
Eidhammer I., Jonassen I., & Taylor WR. Protein Bioinformatics - An Algorithmic Approach to Sequence and Structure Analysis. Wiley, 2004.
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On-line library catalogues
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Time requirements
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All forms of study
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Activities
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Time requirements for activity [h]
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Preparation for the Exam
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60
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Total
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60
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Prerequisites - other information about course preconditions |
- |
Competences acquired |
ability to define fundamental concepts, describe fubdamental approaches applied to structural bioinformatics of proteins |
Teaching methods |
- Monologic Lecture(Interpretation, Training)
- Training in job and motor Skils
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Assessment methods |
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