| Course title | Animal Models of Human Diseases |
|---|---|
| Course code | MTM/VCA21 |
| Organizational form of instruction | Seminar |
| Level of course | Master |
| Year of study | 4 |
| Semester | Winter |
| Number of ECTS credits | 2 |
| Language of instruction | Czech |
| Status of course | Optional |
| Form of instruction | Face-to-face |
| Work placements | This is not an internship |
| Recommended optional programme components | None |
| Course availability | The course is available to visiting students |
| Lecturer(s) |
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| Course content |
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History of animal research. The ethics of animal research. Animal research legislation. Animal facilities, classification and characteristics (conventional, breeding, GMO, SPF), specialised equipment. Animal welfare (laboratory and experimental conditions). Review of laboratory animals, descriptions of the species and strains, their specifics, advantages and disadvantages. Principles of experimental work (handling, labelling, testing, sampling of biological material, drug administration, microsurgery, anaesthesia, euthanasia). Experimental animal models (cancer, metabolic, neurodegenerative, infectious diseases). Case studies of animal models based on selected publications. Visit of the IMTM animal and core imaging facility (X-ray, PET/SPECT/CT, fluorescence, luminescence, ultrasound.
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| Learning activities and teaching methods |
Lecture, Monologic Lecture(Interpretation, Training), Dialogic Lecture (Discussion, Dialog, Brainstorming), Projection (static, dynamic)
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| Learning outcomes |
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The aim of the subject is to provide students with a general overview of the methods of care and experimental work with laboratory animals and their use as study models of human diseases.
Students will gain knowledges about experimental work with laboratory animals and their use in the study of human diseases. |
| Prerequisites |
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Finished the third year of the study.
BIO/VCB11 ----- or ----- BIO/VC011 |
| Assessment methods and criteria |
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Student performance, Dialog, Systematic Observation of Student
Knowledge in the range of course matter and recommended literature and knowledge of animal welfare and basic principles of the animal handling. |
| Recommended literature |
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| Study plans that include the course |
| Faculty | Study plan (Version) | Category of Branch/Specialization | Recommended semester | |
|---|---|---|---|---|
| Faculty: Faculty of Medicine and Dentistry | Study plan (Version): - (2021) | Category: Medical sciences | 4 | Recommended year of study:4, Recommended semester: Winter |
| Faculty: Faculty of Medicine and Dentistry | Study plan (Version): - (2025) | Category: Medical sciences | 4 | Recommended year of study:4, Recommended semester: Winter |