Course: Microbiome and Its Role in the Human Body

« Back
Course title Microbiome and Its Role in the Human Body
Course code LCH/VAB52
Organizational form of instruction Seminar
Level of course Master
Year of study 3
Semester Summer
Number of ECTS credits 2
Language of instruction English
Status of course Optional
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Course availability The course is available to visiting students
Lecturer(s)
  • Jourová Lenka, Mgr. Ph.D.
  • Anzenbacherová Eva, doc. RNDr. CSc.
Course content
Basic information about the microbiome, its role in various diseases and experimental models used to study microbiome. Bacterial metabolism. Microbiome metabolites and their role in the human organism. Microbiome and drug metabolism. Microbiome, inflammation and immunity. The gut-brain axis and the role of the microbiome. Microbiome targeted therapy. Skin microbiome.

Learning activities and teaching methods
Lecture, Monologic Lecture(Interpretation, Training), Dialogic Lecture (Discussion, Dialog, Brainstorming), Work with Text (with Book, Textbook)
Learning outcomes
The aim of the subject is to define the microbiome and explain its role in the human body, especially in pathological processes, from a biochemical point of view. The emphasis is placed on microbial metabolism in the digestive tract and its further impact on the whole organism. The subject builds on knowledge of microbiology and deals with the molecular mechanisms of biochemical processes and their regulation by microbiome and its metabolites.
The student who passes the subject will gain an overview of the importance of the role of microbiome in human health. This information will provide students with a more comprehensive view of physiological and pathological processes in the human body, where in addition to human cells and enzymatic systems, the microbiome and its metabolites play a crucial role.
Prerequisites
Knowledge of biochemistry and mikrobiology.
LCH/VAB20
----- or -----
LCH/ZAB21 and MIK/ZAA12 and MIK/VAB11
----- or -----
MIK/ZAB11

Assessment methods and criteria
Dialog

100 % attendance in seminars.
Recommended literature
  • Haller, D. (2018). The Gut Microbiome in Health and Disease . ISBN-10: 3319905449. Springer International Publishing AG.


Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester
Faculty: Faculty of Medicine and Dentistry Study plan (Version): General Medicine (2018) Category: Medical sciences 3 Recommended year of study:3, Recommended semester: Summer
Faculty: Faculty of Medicine and Dentistry Study plan (Version): Dentistry (2019) Category: Medical sciences 3 Recommended year of study:3, Recommended semester: Summer
Faculty: Faculty of Medicine and Dentistry Study plan (Version): General Medicine (2019) Category: Medical sciences 3 Recommended year of study:3, Recommended semester: Summer
Faculty: Faculty of Medicine and Dentistry Study plan (Version): General Medicine (2021) Category: Medical sciences 3 Recommended year of study:3, Recommended semester: Summer
Faculty: Faculty of Medicine and Dentistry Study plan (Version): Dentistry (2019) Category: Medical sciences 3 Recommended year of study:3, Recommended semester: Summer