| Course title | Immunology |
|---|---|
| Course code | KIM/VC031 |
| Organizational form of instruction | Lecture + Exercise |
| Level of course | Master |
| Year of study | not specified |
| Semester | Summer |
| Number of ECTS credits | 6 |
| Language of instruction | Czech |
| Status of course | Compulsory |
| Form of instruction | Face-to-face |
| Work placements | This is not an internship |
| Recommended optional programme components | None |
| Course availability | The course is available to visiting students |
| Lecturer(s) |
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| Course content |
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Introduction of principles of functioning of the immune system, inherited and antigen specific humoral and cell-mediated immune response, structure of lymphatic system, mechanisms of immune response induction, participating immune cell populations and signalling, genetic basis of antigen specific immune response diversity, HLA molecules, central and peripheral tolerance, mechanisms of induction and regulation of inflammatory response. Explanation of the differences in functioning of systemic and mucosal immune system, mechanisms of immune defense to infection and surveillance of tumor development. Principles of hypersensitivity reactions and clinical examples. Introduction to laboratory immunological investigation, including allergen hypersensitivity investigation, principles of specimens collection from patients, principles of clinical immunology laboratory methods, overview of routinelly investigated immune parameters, indications and their interpretation. HLA polymorphism typing and selected molecular biology methods for investigation in patients with autoimmunity disorders, immune efficiencies or malignancies.
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| Learning activities and teaching methods |
| Lecture, Dialogic Lecture (Discussion, Dialog, Brainstorming), Observation, Demonstration, Projection (static, dynamic), Laboratory Work |
| Learning outcomes |
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Students will learn about the immunological mechanisms, clinical manifestations and possibilities of immunologically-mediated therapy and prevention of diseases with an immunologic mechanisms involved, especially allergic, autoimmune, and oncology diseases and immunodeficiencies. Students will learn about the principles of transplantation. In the field of immunological investigation methods, students will deepen their knowledge of differential diagnostic significance and interpretive potential.
Students will learn about the principles of immune system functioning, about clinical manifestations, laboratory investigation and therapy and prevention of diseases with an immunological component, especially allergic, autoimmune and oncologic diseases and immunodeficiences. |
| Prerequisites |
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Completion of all theoretical subjects.
FAR/VCA32 ----- or ----- FAR/VCB11 and PFY/VCB12 ----- or ----- PFY/VCB21 and MIK/VCA31 ----- or ----- MIK/VCB11 and FYZ/VCA11 ----- or ----- FYZ/VCA21 and FYZ/VCB11 ----- or ----- FYZ/VCB21 |
| Assessment methods and criteria |
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Oral exam
Attendance on all practicals. Credit test. Oral exam. |
| Recommended literature |
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| Study plans that include the course |
| Faculty | Study plan (Version) | Category of Branch/Specialization | Recommended semester | |
|---|---|---|---|---|
| Faculty: Faculty of Medicine and Dentistry | Study plan (Version): - (2025) | Category: Medical sciences | 3 | Recommended year of study:3, Recommended semester: Summer |