Course: Human Physiology and Pathophysiology

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Course title Human Physiology and Pathophysiology
Course code KBC/FPC
Organizational form of instruction Lecture
Level of course Master
Year of study 1
Semester Winter
Number of ECTS credits 3
Language of instruction Czech
Status of course Compulsory, Optional
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Lecturer(s)
  • Friedecká Jaroslava, RNDr. Ph.D.
Course content
1) Physiology (definition, basic tools and principles) and pathophysiology (definition; course, stages and consequences of disease) 2) Etiology (causes of disease - external, internal, risk factors; primary and secondary diseases) 3) Defense systems - inflammation, fever, stress 4) Immune system disorders - immunodeficiency, immunopathological reaction 5) Immunotolerance - failure (allergy, autoimmunity), transplantation, anti-cancer (immune surveillance) 6) Pathophysiology of cancer 7) Hypoxia (definition, causes, consequences, principle of treatment) 8) Blood (red and white blood series, hemostasis) and body fluids 9) Cardiovascular system - heart (basic function, cardiac output, heart failure, blood pressure, cardiomyopathy, cardiac compartment blood flow disorders, cardiac inflammation, IHD, arrhythmias) and blood vessels (function, atherosclerosis, ischemia, thrombosis), lymphatic circulation 10) Respiratory system (function, blood gases, ventilation disorders, lung disease) 11) Excretory system (function, disorders) 12) Digestive system (function, disorders) 13) Endocrine system (functions, disorders) )

Learning activities and teaching methods
Monologic Lecture(Interpretation, Training), Dialogic Lecture (Discussion, Dialog, Brainstorming), Work with Text (with Book, Textbook), Analyzing and producing audiovisual content
  • Attendace - 26 hours per semester
  • Preparation for the Exam - 30 hours per semester
Learning outcomes
Physiology aims to describe the functioning of the healthy human organism at the cellular, tissue and organ levels. It links the biochemical, physical and biological principles of individual processes and discusses their regulation, coordination and integration. Pathophysiology is concerned with the causes (aetiology) and mechanisms of disease development (pathogenesis) and describes changes in the function of the organism and organs during the disease process. Its understanding is essential for the correct choice of diagnostic procedures, treatment (elimination of the cause or intervention in the pathogenesis), prevention and the development of new drugs and therapeutic procedures.
Acquiring knowledge about the functioning of the healthy human organism at the cellular, tissue and organ level, as well as knowledge about the causes and mechanisms of disease development, which is important for the correct choice of diagnostic procedures, treatment, prevention and development of new drugs and therapeutic procedures.
Prerequisites
Základní znalosti z biochemie a fyziologie živočichů.

Assessment methods and criteria
Oral exam, Written exam

Written test and subsequent oral examination The test contains 22 questions (2 from each section). These are matching questions, matching to text, matching to picture and multiple choice questions. The questions have one or more correct answers. Incorrect answers are penalised to avoid guessing. A 68% pass rate is required to pass the written part of the exam. The time limit is 1 hour. You are not allowed to leave the Moodle platform (and search for information in other sources) during the test.
Recommended literature
  • Dylevský, I. (2019). Somatologie pro předmět Základy anatomie a fyziologie člověka. Praha, Grada Publishing, a.s.
  • Hořejší, V., Bartůňková, J., Brdička, T., Špíšek, R. (2013). Základy imunologie. Praha, Stanislav Juhaňák - TRITON.
  • Mourek J. (2012). Fyziologie pro studenty zdravotnických oborů. Praha: Grada.
  • Nečas, E. a kol. (2021). Obecná patologická fyziologie. Praha: Karolinum.
  • Rokyta Richard a kol. Fyziologie. Praha 5. 2016.
  • Vokurka, M. a kol. (2014). Patofyziologie pro nelékařské směry. Praha, Karolinum.


Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester
Faculty: Faculty of Science Study plan (Version): Analytical Biochemist (2024) Category: Chemistry courses 1 Recommended year of study:1, Recommended semester: Winter
Faculty: Faculty of Science Study plan (Version): Biochemistry (2022) Category: Chemistry courses - Recommended year of study:-, Recommended semester: Winter