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Lecturer(s)
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Course content
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Lifespan and aging. Evolution of aging. Mechanistic theories of aging. Aging of biomolecules. Aging of cells. Cell senescence. Aging of tissues and organs. Stress. Damage and reparation. Hormesis. Age-related diseases. Biomarkers. Anti-aging interventions. Genetics of longevity. Premature aging syndroms.
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Learning activities and teaching methods
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Lecture
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Learning outcomes
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Lifespan and aging. Definition. Mechanistic theories of aging. Evolution of aging. Anti-aging interventions.
Describe and explain aging at the level of molecules/cells/tissues/organs/organisms/populations.
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Prerequisites
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Lifespan and aging. Definition. Mechanistic theories of aging. Evolution of aging. Anti-aging interventions.
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Assessment methods and criteria
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Mark
Discussion of 2 topics in the oral exam.
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Recommended literature
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Edward J. Masoro, Steven N. Austad (eds.). (2010). Handbook of the Biology of Aging. Academic Press.
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Nicolas Musi a Peter Hornsby (eds.). (2015). Handbook of the Biology of Aging 8th Edition.. Academic Press (2015).
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Robert Arking. (2019). Biology of Longevity and Aging - pathways and prospects.. Oxford university press (2019).
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Suresh Rattan. (2009). Biogerontology - Compendium to accompany a lecture course on the biology of ageing.
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Suresh Rattan, Peter Kristensen, Brian F. C. Clark (eds.). (2006). Understanding and Modulating Aging. Annals of the New York Academy of Sciences.
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