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Lecturer(s)
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Kryštof Vladimír, prof. RNDr. Ph.D.
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Chamrád Ivo, Mgr. Ph.D.
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Plíhalová Lucie, Mgr. Ph.D.
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Lenobel René, Mgr. Ph.D.
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Voller Jiří, Mgr. Ph.D.
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Berka Karel, doc. RNDr. Ph.D.
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Mik Václav, Mgr. Ph.D.
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Jorda Radek, Mgr. Ph.D.
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Veselá Denisa, Mgr. Ph.D.
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Course content
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Scientific literature. General bibliographic databases (Pubmed, Web of Science, EBSCO, ProQuest, etc.). Full-text databases, general and publisher. Biotechnological and biomedical databases (NCBI, ExPASy, EMBL-EBI, HGNC). Sequence and structure databases. Comparison of nucleic acids and protein sequences. Searching for genes. Functional genomics. Classification of proteins and proteomics. Posttranslational modifications of proteins. Phylogenetic studies and comparative genomics.
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Learning activities and teaching methods
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Lecture, Work with Text (with Book, Textbook), Demonstration, Laboratory Work
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Learning outcomes
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To learn how to work with scientific literature. To learn how to use biological, chemical and biomedical databases.
Scientific literature. General bibliographic databases (Pubmed, Web of Science, EBSCO, ProQuest, etc.). Full-text databases, general and publisher. Biotechnological and medical databases. Sequence and structure databases. Comparison of nucleic acids and protein sequences. Searching for genes. Functional genomics. Classification of proteins and proteomics. Posttranslational modifications of proteins. Phylogenetic studies and comparative genomics.
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Prerequisites
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To learn how to work with scientific literature. To learn how to use biological and chemical databases.
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Assessment methods and criteria
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Written exam, Seminar Work
Full participation at the seminars is required, 80% successfull passing the test
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Recommended literature
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Baxevanis AD, Ouellette BFF. (2004). Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins. WileyBlackwell; 3rd Edition edition.
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Bishop, M.J. (1999). Genetics Databases. Academic Press.
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Claverie, J.M. (2006). Bioinformatics for Dummies. John Wiley & Sons; 2nd Edition edition.
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Sadek, H.A. (2006). Bioinformatics: Principles and Basic Internet Applications. Trafford Publishing.
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