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Lecturer(s)
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Müller Petr, MUDr. Ph.D.
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Vojtěšek Bořivoj, RNDr. DrSc.
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Hrstka Roman, doc. Mgr. Ph.D.
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Jorda Radek, Mgr. Ph.D.
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Course content
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Introduction into cancer cell biology, Genomic approaches in experimental biology, Gene therapy, Protein engineering, Phage display, Protein preparation and purification, Development, characterization and utilization of antibodies, Models in application research, Human biological material in research, Predictive and prognostic pathology, Development, characterization and testing of the drugs, Utilization of viruses in experimental biology.
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Learning activities and teaching methods
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Lecture, Laboratory Work
- Homework for Teaching
- 12 hours per semester
- Preparation for the Exam
- 30 hours per semester
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Learning outcomes
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Development, characterization, methods and testing in experimental biology.
Student should be able to (after attending the course): Introduction into cancer cell biology, Genomic approaches in experimental biology, Gene therapy, Protein engineering, Phage display, Protein preparation and purification, Development, characterization and utilization of antibodies, Models in application research, Human biological material in research, Predictive and prognostic pathology, Development, characterization and testing of the drugs, Utilization of viruses in experimental biology.
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Prerequisites
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unspecified
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Assessment methods and criteria
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Mark
80% fruitfulness on written exam
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Recommended literature
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Alberts, B. a kol. (2002). Molecular Biology of the Cell, 4th ed.. Garland Science, New York.
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Cassimeris L. et al. (2011). Lewin´s cells.. Sudbury: Jones and Bartlett Publishers.
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Douglas Hanahan and Robert A. Weinberg. (2011). Hallmarks of Cancer: The Next Generation. Cell 144.
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Hammers C., M., Stanley J., R.. (2014). Antibody Phage Display: Technique and Applications. Journal of Investigative Dermatology.
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Harlow, E., Lane, D. (1999). Using antibodies. Cold Spring Harbor, New York.
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Klinická onkologie 2014 Supplementum. (2014). Postupy a metody v aplikoané molekulární onkologii?.
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Krejsek, J. a kol. (2004). Klinická imunologie. Nucleus HK.
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Robert A. (2009). Antibody Phage Display: Methods and Protocols. A product of Humana Press,.
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Robert A. Weinberg. (2013). The Biology of Cancer. Second Edition,.
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Slabý, O., et al. (2015). Molekulární medicína. Praha Galén.
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