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Lecturer(s)
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Šafářová Dana, Mgr. Ph.D.
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Course content
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Introduction into genetics. Cytological basics of inheritance - cell, cell divisions, chromosomes. Mendel´s principles of inheritance, G. Mendel. Application of mendelian inheritance - gene interactions, epistasis. Sex determination, basic genetic and environmental models. Gene linkage, T.H. Morgan, gene mapping. Molecular basics of inheritance - nucleic acids. Flow of genetic information, Central dogma - replication, transcription, translation. Mutations. Population genetics - Hardy-Weinberg equilibrium. Human Genetics. Conservation genetics.
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Learning activities and teaching methods
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Monologic Lecture(Interpretation, Training), Dialogic Lecture (Discussion, Dialog, Brainstorming), Laboratory Work
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Learning outcomes
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Student is able to (after attending the course): - Explain the principles of Mendelian genetics and their exceptions - describe the chromosomal basis of inheritance, and explain the principle and the importance of mitosis and meiosis - explain the principles of sex determination and inheritance of sex linked marks - describe the molecular principles of inheritance, characterise the nucleic acids and the principle of gene information flow - describe the basis of population genetics, Hardy-Weinberg equilibrium and factors affecting the HW balance - use and explain regular genetic terms and consequencies
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Prerequisites
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unspecified
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Assessment methods and criteria
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Oral exam, Student performance
Oral exam (3 randomly chosen questions)
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Recommended literature
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Alberts. (2000). Základy buněčné biologie. Ústí na Labem.
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Šafářová, D. (2011). Kapitoly z obecné genetiky. Olomouc: Univerzita Palackého v Olomouci.
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