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Lecturer(s)
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Modrianský Martin, prof. Mgr. Ph.D.
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Bartek Josef, doc. MUDr. CSc.
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Course content
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Disorders of internal milieu. Acido-base equilibrium. Water metabolism and electrolytes. Therapeutical calculations. Case histories.
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Learning activities and teaching methods
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Monologic Lecture(Interpretation, Training), Dialogic Lecture (Discussion, Dialog, Brainstorming), Work with Text (with Book, Textbook), Demonstration, Projection (static, dynamic)
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Learning outcomes
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The aim of the subject is to explain teoretical principles of biochemistry, clinical biochemistry and regulatory mechanisms of basic metabolic pathways. This knowledge is essential for interpretation of physiological and pathological events in human organism. Students are also trained in laboratory classes to master simple biochemical analyses and to interpret the results of laboratory tests in differential diagnostics and therapy.
The student who passes the subject will be equipped with theoretical knowledge on basic biochemical pathways and information on regulation of intermediary metabolism. Student will be able to interpret physiological and pathological events in human prganism. In practice, students will be able to work according to good laboratory practice rules and to perform basic biochemical tests and to interpret laboratory results in a procedure of differential diagnosis and therapy. By acquiring all above mentioned skills the student will be able to utilize them in specialized fields of internal medicine that will follow.
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Prerequisites
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Basic knowledge of high school biochemistry.
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Assessment methods and criteria
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Mark, Oral exam, Seminar Work
Test.
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Recommended literature
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Henry, J.B. (2001). Clinical Diagnosis and Management by Laboratory Methods. Sounders.
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Chlup, R., Bartek, J. (1996). Programová léčba diabetu. Praha - Galén.
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Masopust, J. (1998). Klinická biochemie - požadování a hodnocení biochemických vyšetření ( 1. a 2. díl ). Karolinum.
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Matouš, B. (2010). Základy lékařské chemie a biochemie. Galén.
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Racek, J. (2006). Klinická biochemie. Praha, Galén.
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Stejskal, D., Stejskal, P., Bartek, J., Mohapl, P. (1996). Metabolická onemocnění hromadného výskytu - metabolický kardiovaskulární syndrom, osteoporoza, urolitiáza.. Biovendor.
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Štern, P. a kol. (2005). Obecná a klinická biochemie pro bakalářské obory studia. Karolinum Praha.
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Wagner, P. (2003). Laboratorní referenční hodnoty. Triton.
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Zámečník, M., Jabor, A. (2005). Preanalytická fáze. SKB ČLS JEP.
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Zima T. a kol. (2007). Laboratorní diagnostika. Galén, Praha.
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