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Lecturer(s)
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Ulrichová Jitka, prof. RNDr. CSc.
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Gucký Tomáš, RNDr. Ph.D.
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Kopečný David, Mgr. Ph.D.
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Course content
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Introduction to clinical biochemistry, reference values, analytical and biological errors of laboratory measurements, good laboratory practice. Urine I. Collection, conservation, physical measurements, chemical analysis: protein assay, blood, bile pigments Bile stones. Urine II. Assay of keto-compounds, glucose, nitrites. Urine sediment, Hamburger examination. Examination of renal functions. Examination of liver functions. Diabetes mellitus, oGTT, self monitoring, waste of glucose in urine, blood analysis of patient on glucometer, diabetic documentation, analysis of glycaemia using glucometer ONE-TOUCH, oGTT design and interpretation of results, techniques and design of analysis of glycaemia, glycosylated haemoglobin and glycosylated proteins. Interpretation. Acidobasic balance (ABR), collection of material, types of disorders: ABR, Dif. Dg. disorder ABR, Metabolism of ions, natrium, calcium. Gestational assay, HCG. Infarct of myocardium. Cardiomarkers troponin, myoglobin, CKMB-mas. Hyperlipoproteinemie, atherosclerosis, aetiology of atherosclerosis, metabolic syndrome, risk factors atherosclerosis, therapy. Lipid consulting.
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Learning activities and teaching methods
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Lecture, Dialogic Lecture (Discussion, Dialog, Brainstorming), Projection (static, dynamic)
- Homework for Teaching
- 20 hours per semester
- Attendace
- 24 hours per semester
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Learning outcomes
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Introduction to clinical biochemistry, reference values, analytical and biological errors of laboratory measurements, good laboratory practice.
Describe and explain: Introduction to clinical biochemistry, reference values, analytical and biological errors of laboratory measurements, good laboratory practice. Urine I. Collection, conservation, physical measurements, chemical analysis: protein assay, blood, bile pigments Bile stones. Urine II. Assay of keto-compounds, glucose, nitrites. Urine sediment, Hamburger examination. Examination of renal functions. Examination of liver functions. Diabetes mellitus, oGTT, self monitoring, waste of glucose in urine, blood analysis of patient on glucometer, diabetic documentation, analysis of glycaemia using glucometer ONE-TOUCH, oGTT design and interpretation of results, techniques and design of analysis of glycaemia, glycosylated haemoglobin and glycosylated proteins. Interpretation. Acidobasic balance (ABR), collection of material, types of disorders: ABR, Dif. Dg. disorder ABR, Metabolism of ions, natrium, calcium. Gestational assay, HCG. Infarct of myocardium. Cardiomarkers troponin, myoglobin, CKMB-mas. Hyperlipoproteinemie, atherosclerosis, aetiology of atherosclerosis, metabolic syndrome, risk factors atherosclerosis, therapy. Lipid consulting.
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Prerequisites
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unspecified
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Assessment methods and criteria
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Mark, Written exam
60% fruitfulness in exam test
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Recommended literature
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Ferenčík M., Rovenský J., Nyulassy Š. (2004). Ilustrovaný imunologický slovník. Galén 2004.
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Jabor A. (2008). Vnitřní prostředí. Grada Publishing,a.s.
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Jabor A, Zámečník M. (2005). Preanalytická fáze. ČSKB ČLS JEP a SEKK.
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Koolman J., Rohm KH.:. (2012). Barevný atlas biochemie, 4.vydání. Grada 2012.
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Masopust, J. (1998). Klinická biochemie - požadování a hodnocení biochemických vyšetření, 1. a 2. díl. Praha - Karolinum, UK.
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Petr Wagner. Laboratorní referenční hodnoty. Triton, 2003.
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Racek, J. (1999). Klinická biochemie. Galén, Praha.
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Schneiderka P. a kol. (2004). Kapitoly z klinické biochemie.. Karolinum Praha 2004.
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Svačina Š. (2010). Poruchy metabolismu a výživy. Galén 2010.
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Štern P a kol.:. (2005). Obecná a klinická biochemie pro bakalářské obory studia. Karolinum Praha 2005.
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Zima T. et al.:. (2007). Laboratorní diagnostika, druhé vydání.. Galén, 2007.
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3. Stejskal D., Stejskal P., Bartek J., Mohapl P. (1996). Metabolická onemocnění hromadného výskytu - metabolický kardiovaskulární syndrom, osteoporoza, urolitiáza,. Biovendor 1996.
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4. Chlup R., Bartek J. aj. (1996). Programová léčba diabetu. Galén 1996.
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5. Berger M., Jorgens V., Chlup R. Léčba inzulinem v každodenním životě. Victoria Publishing, 1995.
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7. Češka R. (2012). Cholesterol a ateroskleróza, léčba dyslipidémií. Triton 2012.
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