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Lecturer(s)
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Frébort Ivo, prof. RNDr. CSc., Ph.D.
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Course content
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Genetics. Reproduction as the principle of inheritance. Classical genetic analysis. Mendel genetics. Quantity and structures of chromosomes. Chromosome mapping. Molecular biology of genes, DNA and molecular structures of chromosomes. Replication of DNA and chromosomes. Transcription and posttranscriptional modification of RNA. Genetic code and translation. Mutation, repair and recombination of DNA. Definition of a gene. Genetics of viruses and bacteria. Mobile genetic elements, transposons. Genetics of mitochondria and chloroplasts. Techniques of molecular genetics, genomics. Molecular analysis of genes and their products. Regulation of gene expression in viruses and prokaryotes. Regulation of gene expression in eukaryotes. Genetic control of biological processes. Genetic control of animal development. Genetic control of behavior. Genetic control of vertebrate immune system. Genetic principle of cancer. Population and developmental genetics.
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Learning activities and teaching methods
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Dialogic Lecture (Discussion, Dialog, Brainstorming)
- Preparation for the Exam
- 50 hours per semester
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Learning outcomes
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Obtaining advanced knowledge in the field of genetics.
Summarize knowledge in the field of molecular genetics, explain techniques of molecular genetics.
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Prerequisites
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The course is intended for doctoral students in Biochemistry.
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Assessment methods and criteria
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Dialog
The candidate is expected to conduct scientific discussion in broader context of the whole discipline.
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Recommended literature
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Snustad, D.P., Simmons, M.J. (2000). Principles of genetics, 2nd ed.. John Wiley & Sons, New York, USA.
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