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Lecturer(s)
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Šebela Marek, prof. Mgr. Dr.
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Luhová Lenka, doc. RNDr. Ph.D.
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Course content
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Structure and function of proteins. Enzymes and hemoglobin. Carbohydrates. Lipids and cell membranes. Catalytic strategies. Regulatory strategy. Regulation of metabolic pathways: glycolysis and gluconeogenesis, citrate cycle, oxidative phosphorylation, photosynthesis light reactions, Calvin cycle, pentosaphosphate pathway, glycogen metabolism, fatty acid metabolism, protein turnover and amino acid catabolism, amino acid biosynthesis, biosynthesis and nucleotide degradation. DNA replication, recombination and repair. Synthesis of RNA and their function. Synthesis of proteins. Function of tRNA, mRNA and ribosomes. Prokaryotic and eukaryotic protein synthesis. Protein biosynthesis inhibitors. Gene expression control. Integration and regulation of mammalian energy metabolism.
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Learning activities and teaching methods
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Dialogic Lecture (Discussion, Dialog, Brainstorming)
- Preparation for the Exam
- 50 hours per semester
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Learning outcomes
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Get possession of complex and substantial knowledges of metabolic patheways, reciprocal interconnection and regulation.
Associate information, interpret experimental data, solve problems, report on novelties in biochemistry
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Prerequisites
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Successful graduated studium of Bachelor of Science and Magister of Science in Biochemistry.
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Assessment methods and criteria
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Oral exam
the candidate is expected to conduct scientific discussion in broader context of the whole discipline.
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Recommended literature
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Buchanan, B. B., Gruissem, W., Jones, R. L. (2015). Biochemistry and Molecular Biology of Plants. Courier Companies, USA.
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Dey, P. M., Harborne, J. B. (1997). Plant Biochemistry. Academic Press.
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Heldt, H. W. (2010). Plant Biochemistry (4. vydání). Elsevier Academic Press, San Diego.
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Jones, R, Ougham, H., Thomas, H., Waaland, S. (2013). The molecular life of plants. Chichester: Wiley-Blackwell.
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Prasad, B. D., Sahni, S., Kumar, P., Siddiqui, M. W. (2018). Plant Biotechnology. Taylor & Francis.
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