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Lecturer(s)
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Luhová Lenka, doc. RNDr. Ph.D.
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Course content
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Diversity of metabiolism. Autotrophic, heterotrophicf, chemotrotrophicf, phototrophic and another organisms. Status of oxygen in the metabolisms. Aerobic, anaerobic, obligatory aerobic and anaerobic organisms, facultative anaerobic organisms and another. Anabolisms and catabolisms. Thermodynamic of biological systems. Function of enzymes in the organisation of katabolic and anabolic ways. Regulation of metabolisms. Amfibolic intermediate products. Adenosinetriphosphate cycle. Part of nicotinamides koenzyms in the anabolic and catabolic metabolic ways. Methods of experimental study of metabolic ways. Sacharide metabolisms. Lipide metabolisms. Proteine metabolisms. Nucleotide metabolisms. Type of signal molecules and intercellular signalisation of eukaryotes. Metabolisms of hormons and basic experimetal methods study their effect. Mechanisms of transmission signals mediated by outer receptors. Heterotrimeric trnsduction G-proteins a their function. Integration of metabolisms and unidirection of metabolic ways. .
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Learning activities and teaching methods
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Lecture
- Preparation for the Exam
- 85 hours per semester
- Attendace
- 26 hours per semester
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Learning outcomes
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Generalization of metabolic pathways, methods of metabolism regulation cells trasport systeme and metabolism of glykogene.
Define main general metabolic patheways, describe general metabolic processes, their contexture and regulations.
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Prerequisites
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Successful graduation fundamentals of chemistry and mainly fundamentals of biochemistry.
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Assessment methods and criteria
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Written exam
Written exam, 1 hour, 8 tasks; 24 points A 24-22 B 21-18 C 17-16 D 15-14 E 13-12 F less than 12
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Recommended literature
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Devlin T. M. (2011). Textbook of biochemistry with clinical correlations. USA.
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Ferrier D. S. (2018). Biochemistry (7th ed.). Walters Kluwer.
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Voet, D., & Voet, J. G. (2011). Biochemistry. Hoboken, N.J: John Wiley & Sons.
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