|
Lecturer(s)
|
|
|
|
Course content
|
Basic toxicology. Molecular mechanisms of toxicity, Effect of pollutants at the cellular and organism level. Biotransformation. Carcinogenicity, mutagenicity and teratogencity. Toxicity testing. Inorganic pollutants, organic pollutants. Environmental toxicology. Pollutants in ecosystems. Biomarkers, biomonitoring. Bhopal, Seveso, Černobyl.
|
|
Learning activities and teaching methods
|
Lecture, Dialogic Lecture (Discussion, Dialog, Brainstorming), Projection (static, dynamic)
- Attendace
- 24 hours per semester
|
|
Learning outcomes
|
The aim is to introduce students to the basic principles of toxicology and ecotoxicology.
Knowledge Recall basic toxicological terminology Describe molecular mechanism of toxicity, biotransformation, carcinogenity, toxicity testing.
|
|
Prerequisites
|
Elementary knowledge in chemistry
|
|
Assessment methods and criteria
|
Mark, Written exam, Seminar Work
Exam - knowledge and good orientation in subjects, dataresearch in toxicology databases.
|
|
Recommended literature
|
-
Barnet, I., & Hanslík, E. (2012). Radioaktivní látky v životním prostředí. Chrudim: Vodní zdroje Ekomonitor.
-
Jorgensen, S., E. Ecotoxicology. Elsevier AP, Amsterdam, 390p., 2010..
-
Kijovská, L. (2013). Ekotoxikológia vo vodnom hospodárstve Slovenska. Bratislava: Nakladateľstvo STU.
-
Matrka, M., Rustek, V. (1991). Průmyslová toxikologie. VŠCHT Pardubice, 157 s.
-
Picka, K., Matoušek, J. (1996). Základy obecné a speciální toxikologie.. MŽPČR Praha, 103 s.
-
Prokeš, J. a kol. (1997). Základy toxikologie.. Karolinum UK Praha, 165 s.
-
SMITH, R. P. (1992). Envitonmental Toxicology. Lea & Febiger, Philadelphia, 300 pp.
-
Tichý, M. (1998). Toxikologie pro chemiky,. Karolinum UK Praha, 90 s.
-
WALKER, C.,H. (2001). Principles of Ecotoxicology. Taylor & Francis, London, 309 pp.
|