Course: Basics of pharmaceutical chemistry

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Course title Basics of pharmaceutical chemistry
Course code ACH/ZCHEL
Organizational form of instruction Lecture
Level of course Master
Year of study not specified
Semester Summer
Number of ECTS credits 2
Language of instruction Czech
Status of course Optional
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Lecturer(s)
  • Pluháček Tomáš, RNDr. Ph.D.
Course content
Introduction to pharmaceutical chemistry, definitions, areas of pharmacology, introduction to pharmaceutical chemistry, medicine formulations, general pharmacology, pharmacokinetics, pharmacodynamics, metabolism of drugs, development of new drugs, search for biologically active compounds, combinatorial chemistry, molecular modelling, isolation of active substances from natural sources, safety testing and regulations, registration, good laboratory practice, control bodies, applied pharmacology, analgesics, drugs affecting central nervous systems, drugs affecting vegetative nervous systems, local anesthetics, muscle relaxants, anti-allergic drugs and antihistamines, treatment of blood circulation system, treatment of digestive and elimination system, antitussives, therapy and prevention of infectious and parasite diseases, cytostatic drugs, vitamins, hormones, modern drugs, biodrugs, molecular biology in drug development, basics of molecular biology for chemists, cellular therapy, gene therapy

Learning activities and teaching methods
Monologic Lecture(Interpretation, Training), Dialogic Lecture (Discussion, Dialog, Brainstorming)
  • Attendace - 26 hours per semester
  • Preparation for the Exam - 34 hours per semester
Learning outcomes
The aim of this course is to introduce to students basics of pharmaceutical chemistry.
to describe basics of general and applied pharmacology; to describe approaches for development of new drugs and their registration
Prerequisites
The knowledge of basics of organic chemistry.

Assessment methods and criteria
Written exam

A student should be able to present basic facts about taught themes, especially about general and applied pharmacology. The examination is done by a written test where a student should obtain at least 60 % of points.
Recommended literature
  • (2009). Český lékopis. MZ ČR.
  • Fusek M., Vítek L., Blahoš J., Hajdúch M., Ruml T. a kol. (2012). Biologická léčiva. Grada.
  • Hampl F., Rádl S., Paleček J. (2010). Farmakochemie. VŠCHT Praha.
  • Komárek P., Rabišková a kol. (2006). Technologie léků. Galén.
  • Lincová D., Farghali a kol. (2007). Základní a aplikovaná farmakologie. Galén.
  • Lullman H., Mohr K., Hein L. (2012). Barevný atlas farmakologie. Grada.
  • Martínková J. a kol. (2007). Farmakologie pro studenty zdravotnických oborů. Grada.


Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester
Faculty: Faculty of Science Study plan (Version): Analytical Chemistry (2021) Category: Chemistry courses 1 Recommended year of study:1, Recommended semester: Summer