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Lecturer(s)
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Barták Petr, prof. RNDr. Ph.D.
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Course content
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Analysis of organic compounds Sample characterization, sampling, preparatory operations, drying, purity characterization, appearance examination. Physico-chemical constants (melting point, boiling point, density, refractive index, specific rotation, solubility, partition coefficient) and their relations to the chemical structure. Instrumental methods of chemical analysis - spectrometric methods (UV-Vis spectrometry, infrared spectrometry, nuclear magnetic resonance, mass spectrometry, optical rotary dispersion), electrochemical methods (voltammetry, coulometry) separation methods (extraction, gas chromatography, liquid chromatography, electrophoresis, isotachophoresis). Organic elemental analysis. Principles and techniques of proofs, identification and determination of organic compounds and their mixtures. General principles of classical methods of organic analysis. Titrations in non-aqueous media. Proof and determination of functional groups - hydrocarbons, hydroxycompounds, carbonylcompounds, carboxylic acids and their functional derivatives, nitrogen containing compounds, sulphur containing compounds, halogen containing compounds, selected polyfunctional derivatives. Instrumental methods and their application for particular groups of organic compounds. Analytical derivatization.
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Learning activities and teaching methods
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Lecture, Dialogic Lecture (Discussion, Dialog, Brainstorming)
- Attendace
- 78 hours per semester
- Homework for Teaching
- 52 hours per semester
- Preparation for the Course Credit
- 30 hours per semester
- Preparation for the Exam
- 50 hours per semester
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Learning outcomes
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The aim is to familiarize with facilities of analysis of organic compounds.
Associate information, interpret experimental data, solve problems, interpret the structure of substances on the basis of spectral data and chemical reactivity
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Prerequisites
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The knowledge of basics of organic and analytical chemistry is recommended.
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Assessment methods and criteria
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Oral exam, Written exam
Requirement: active attendance in seminars (75 %), written seminar work (seminar), oral exam (lecture) Requirement: active attendance in seminars (75 %), examination paper (seminar), oral exam (lecture)
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Recommended literature
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Beyerman K.. (1987). Organická stopová analýza. SNTL Praha.
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Harvey D. (2000). Modern Analytical Chemistry. McGraw-Hill, New York.
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Christian G.D., Dasqupta P.K., Schug K.A. (2014). Analytical chemistry 7th. ed.. Wiley Hoboken.
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Churáček J. a kol. (1993). Nové trendy v teorii a instrumentaci vybraných analytických metod. Praha.
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I. Wilson, C. Poole, M. Cooke. (2000). Encyclopedia of separation science. Academic Press, San Diego, London, Boston, New York, Sydney, Tokyo, Toronto.
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Jandera P. (1999). Atomová a molekulová spektroskopie se zaměřením na stopovou analýzu kontaminantů, díl B. Univerzita Pardubice.
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J.R. Mohrig, Ch.N. Hammond, P.F. Schatz. (2010). Techniques in Organic Chemistry. W.H. Freeman and Company, New York.
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Jureček M. (1957). Organická analysa I a II. Nakladatelství ČSAV Praha.
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Jureček M.. (1950). Organická analýza. Praha.
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Kellner R., Mermet J.-M., Otto M., Valcárcel M., Widmer, H. M. (2004). Analytical Chemistry. A Modern Approach to Analytical Science. Wiley-VCH, Weinheim.
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maloň P., Podlaha J., Ubik K. (2000). Fyzikálně chemické metody 1-3. AVČR.
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McMurry J. (2007). Organická chemie. Praha.
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Němcová I., Engst P., Jelínek J., Sejbal J. (1998). Spektrometrické analytické metody II. Karolinum.
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Pavia D.L., lampman G.M., Hriz G.S., Engel R.G. (2011). A Small Scale Approach to organic Laboratory Techniques. belmont.
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Shriner R. a kol. (2004). The systematic identification of organic compounds. Wiley Hoboken.
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Stránský Z. a kol. (1981). Analýza organických sloučenin. RUP Olomouc.
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Štulík K., Ševčík J., Pacáková V., Jelínek I., Coufal P., Bosáková Z. (2004). Analytické separační metody. Karolinum Praha.
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Večeřa M., Gasparič J. (1971). Detection and identification of organic compounds. Plenum Press.
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Večeřa M., Gasparič J. (1963). Důkaz a identifikace organických látek. Praha.
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Veibel S. (1963). Praktická příručka organické analýzy. Praha.
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